S506
- Evidence of significant blunt or penetrating trauma AND
- Age ≥16 y.o. AND
- Presence of hemodynamic instability AND
- Sustained SBP <90 or <100 if age >55 AND
- Sustained heart rate >110 AND
- Time since injury is KNOWN to be <3 hours
- Mix 1 g TXA in 100 ml of 0.9% NaCl or LR and infuse over approximately 10 minutes IV or IO
- Use a dedicated line
- Notify receiving trauma center